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1

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

Miess, Heike, Dankworth, Beatrice, Gouw, Arvin M., Rosenfeldt, Mathias, Schmitz, Werner, Jiang, Ming, Saunders, Becky, Howell, Michael, Downward, Julian, Felsher, Dean W., Peck, Barrie, Schulze, Almut

Journal:

Year:

2018

Language:

english

File:

PDF, 1.89 MB

english, 2018

2

Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for In Vivo Cancer Therapy

Zhuang Liu, Alice C. Fan, Kavya Rakhra, Sarah Sherlock, Andrew Goodwin, Xiaoyuan Chen, Qiwei Yang, Dean W. Felsher, Hongjie Dai

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

3

Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for In Vivo Cancer Therapy

Zhuang Liu, Alice C. Fan, Kavya Rakhra, Sarah Sherlock, Andrew Goodwin, Xiaoyuan Chen, Qiwei Yang, Dean W. Felsher, Hongjie Dai

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

4

Autochthonous liver tumors induce systemic T cell tolerance associated with T cell receptor down-modulation

Jasmin T. Ney, Thomas Schmidt, Christian Kurts, Qi Zhou, Dawid Eckert, Dean W. Felsher, Hubert Schorle, Percy Knolle, Thomas Tüting, Winfried Barchet, Reinhard Büttner, Andreas Limmer, Ines Gütgemann

Journal:

Year:

2009

Language:

english

File:

PDF, 2.93 MB

english, 2009

5

Development of a Micro-Computed Tomography–Based Image-Guided Conformal Radiotherapy System for Small Animals

Hu Zhou, Manuel Rodriguez, Fred van den Haak, Geoffrey Nelson, Rahil Jogani, Jiali Xu, Xinzhi Zhu, Yongjiang Xian, Phuoc T. Tran, Dean W. Felsher, Paul J. Keall, Edward E. Graves

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 1.51 MB

english, 2010

6

Tumor dormancy and oncogene addiction

DEAN W. FELSHER

Journal:

Year:

2008

Language:

english

File:

PDF, 341 KB

english, 2008

7

Myc and a Cdk2 senescence switch

van Riggelen, Jan, Felsher, Dean W.

Journal:

Nature Cell Biology

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

8

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

Traykova-Brauch, Milena, Schönig, Kai, Greiner, Oliver, Miloud, Tewfik, Jauch, Anna, Bode, Manja, Felsher, Dean W, Glick, Adam B, Kwiatkowski, David J, Bujard, Hermann

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 1.16 MB

english, 2008

9

Opinion: Cancer revoked: oncogenes as therapeutic targets

Felsher, Dean W.

Journal:

Nature Reviews Cancer

Year:

2003

Language:

english

File:

PDF, 2.31 MB

english, 2003

10

MYC as a regulator of ribosome biogenesis and protein synthesis

van Riggelen, Jan, Yetil, Alper, Felsher, Dean W.

Journal:

Nature Reviews Cancer

Year:

2010

Language:

english

File:

PDF, 436 KB

english, 2010

11

Comparative genomic hybridization on mouse cDNA microarrays and its application to a murine lymphoma model

Sander, Sandrine, Bullinger, Lars, Karlsson, Asa, Giuriato, Sylvie, Hernandez-Boussard, Tina, Felsher, Dean W, Pollack, Jonathan R

Journal:

Year:

2005

Language:

english

File:

PDF, 429 KB

english, 2005

12

HIF-2α Suppresses p53 to Enhance the Stemness and Regenerative Potential of Human Embryonic Stem Cells

Bikul Das, Reza Bayat-Mokhtari, Micky Tsui, Shamim Lotfi, Rika Tsuchida, Dean W. Felsher, Herman Yeger

Journal:

Year:

2012

Language:

english

File:

PDF, 1.47 MB

english, 2012

13

HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo

Ping Gao, Huafeng Zhang, Ramani Dinavahi, Feng Li, Yan Xiang, Venu Raman, Zaver M. Bhujwalla, Dean W. Felsher, Linzhao Cheng, Jonathan Pevsner, Linda A. Lee, Gregg L. Semenza, Chi V. Dang

Journal:

Year:

2007

Language:

english

File:

PDF, 920 KB

english, 2007

14

CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation

Kavya Rakhra, Pavan Bachireddy, Tahera Zabuawala, Robert Zeiser, Liwen Xu, Andrew Kopelman, Alice C. Fan, Qiwei Yang, Lior Braunstein, Erika Crosby, Sandra Ryeom, Dean W. Felsher

Journal:

Year:

2010

File:

PDF, 33 KB

2010

15

CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation

Kavya Rakhra, Pavan Bachireddy, Tahera Zabuawala, Robert Zeiser, Liwen Xu, Andrew Kopelman, Alice C. Fan, Qiwei Yang, Lior Braunstein, Erika Crosby, Sandra Ryeom, Dean W. Felsher

Journal:

Year:

2010

Language:

english

File:

PDF, 3.17 MB

english, 2010

16

Treatment of higher risk myelodysplastic syndrome patients unresponsive to hypomethylating agents with ON 01910.Na

Mahesh Seetharam, Alice C. Fan, Mai Tran, Liwen Xu, John P. Renschler, Dean W. Felsher, Kunju Sridhar, Francois Wilhelm, Peter L. Greenberg

Journal:

Leukemia Research

Year:

2012

Language:

english

File:

PDF, 395 KB

english, 2012

17

Conditional animal models: a strategy to define when oncogenes will be effective targets to treat cancer

Sylvie Giuriato, Karen Rabin, Alice C Fan, Catherine M Shachaf, Dean W Felsher

Journal:

Seminars in Cancer Biology

Year:

2004

Language:

english

File:

PDF, 292 KB

english, 2004

18

Oncogenes as therapeutic targets

Dean W. Felsher

Journal:

Seminars in Cancer Biology

Year:

2004

Language:

english

File:

PDF, 25 KB

english, 2004

19

Conditional transgenic models define how MYC initiates and maintains tumorigenesis

Constadina Arvanitis, Dean W. Felsher

Journal:

Seminars in Cancer Biology

Year:

2006

Language:

english

File:

PDF, 161 KB

english, 2006

20

Conditionally MYC:insights from novel transgenic models

Constadina Arvanitis, Dean W. Felsher

Journal:

Year:

2005

Language:

english

File:

PDF, 110 KB

english, 2005

21

Reversibility of oncogene-induced cancer

Journal:

Current Opinion in Genetics & Development

Year:

2004

Language:

english

File:

PDF, 157 KB

english, 2004

22

162. Oval Cell Expansion Through Wnt Signaling Shortens Tumor Latency During MYC Induced Hepatocarcinogenesis

Masashi Kurobe, Min Hu, Shelly Beer, Saif Ghole, Yeon Jun Jeong, Dean Felsher, Karl G. Sylvester

Journal:

Journal of Surgical Research

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

23

Rehabilitation of cancer through oncogene inactivation

Catherine M. Shachaf, Dean W. Felsher

Journal:

Trends in Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 1.05 MB

english, 2005

24

Reversible Tumorigenesis by MYC in Hematopoietic Lineages

Dean W. Felsher, J.Michael Bishop

Journal:

Year:

1999

Language:

english

File:

PDF, 622 KB

english, 1999

25

The Neuronal Expression of MYC Causes a Neurodegenerative Phenotype in a Novel Transgenic Mouse

Hyoung-gon Lee, Gemma Casadesus, Akihiko Nunomura, Xiongwei Zhu, Rudy J. Castellani, Sandy L. Richardson, George Perry, Dean W. Felsher, Robert B. Petersen, Mark A. Smith

Journal:

The American Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 674 KB

english, 2009

26

A rapid method for the purification of monomeric and/or dimeric phospholipases A2 in crotalid snake venoms

William Welches, Dean Felsher, William Landshulz, John M. Maraganore

Journal:

Year:

1985

Language:

english

File:

PDF, 466 KB

english, 1985

27

c-Myc, MHCI, and NK Resistance in Immunodeficiency Lymphomas

JONATHAN BRAUN, DEAN W. FELSHER, LEE A. GOODGLICK

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 134 KB

english, 1992

28

A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice

Alice C Fan, Marianna M Goldrick, Jennifer Ho, Yu Liang, Pavan Bachireddy, Dean W Felsher

Journal:

Molecular Cancer

Year:

2008

Language:

english

File:

PDF, 804 KB

english, 2008

29

Role of MYCN in retinoblastoma

Felsher, Dean W

Journal:

The Lancet Oncology

Year:

2013

Language:

english

File:

PDF, 118 KB

english, 2013

30

Hepatotoxin-Induced Changes in the Adult Murine Liver Promote MYC-Induced Tumorigenesis

Beer, Shelly, Komatsubara, Kimberly, Bellovin, David I., Kurobe, Masashi, Sylvester, Karl, Felsher, Dean W., Klefstrom, Juha

Journal:

Year:

2008

Language:

english

File:

PDF, 487 KB

english, 2008

31

High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation

Wu, Angela R., Kawahara, Tiara L.A., Rapicavoli, Nicole A., Riggelen, Jan van, Shroff, Emelyn H., Xu, Liwen, Felsher, Dean W., Chang, Howard Y., Quake, Stephen R.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

32

Metabolic changes in cancer cells upon suppression ofMYC

Elena Anso, Andrew R Mullen, Dean W Felsher, José M Matés…

Journal:

Cancer & Metabolism

Year:

2013

Language:

english

File:

PDF, 301 KB

english, 2013

33

Angiocrine Factors Deployed by Tumor Vascular Niche Induce B Cell Lymphoma Invasiveness and Chemoresistance

Cao, Zhongwei, Ding, Bi-Sen, Guo, Peipei, Lee, Sharrell B., Butler, Jason M., Casey, Stephanie C., Simons, Michael, Tam, Wayne, Felsher, Dean W., Shido, Koji, Rafii, Arash, Scandura, Joseph M., Rafii,

Journal:

Year:

2014

Language:

english

File:

PDF, 6.84 MB

english, 2014

34

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

Ye, Deju, Shuhendler, Adam J., Cui, Lina, Tong, Ling, Tee, Sui Seng, Tikhomirov, Grigory, Felsher, Dean W., Rao, Jianghong

Journal:

Nature Chemistry

Year:

2014

Language:

english

File:

PDF, 9.65 MB

english, 2014

35

An essential role for the immune system in the mechanism of tumor regression following targeted oncogene inactivation

Casey, Stephanie C., Li, Yulin, Felsher, Dean W.

Journal:

Immunologic Research

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

36

Noncanonical roles of the immune system in eliciting oncogene addiction

Casey, Stephanie C, Bellovin, David I, Felsher, Dean W

Journal:

Current Opinion in Immunology

Year:

2013

Language:

english

File:

PDF, 831 KB

english, 2013

37

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

Kapanadze, Tamar, Gamrekelashvili, Jaba, Ma, Chi, Chan, Carmen, Zhao, Fei, Hewitt, Stephen, Zender, Lars, Kapoor, Veena, Felsher, Dean W., Manns, Michael P., Korangy, Firouzeh, Greten, Tim F.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 809 KB

english, 2013

38

603 NANO-SCALE PROTEOMIC PROFILING TO DEFINE DIAGNOSTIC SIGNATURES AND BIOMARKERS OF THERAPEUTIC ACTIVITY IN RCC

Leppert, John, Fan, Alice, Liliental, Joanna, Xu, Liwen, Thong, Alan, Yost, Christine, Yaghi, Alia, Metzner, Thomas, Brooks, James, Harshman, Lauren, Sabatti, Chiara, Srinivas, Sandy, Felsher, Dean

Journal:

The Journal of Urology

Year:

2013

Language:

english

File:

PDF, 61 KB

english, 2013

39

Transient Excess of MYC Activity Can Elicit Genomic Instability and Tumorigenesis

Dean W. Felsher and J. Michael Bishop

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.19 MB

english, 1999

40

Reversing Cancer From Inside and Out: Oncogene Addiction, Cellular Senescence, and the Angiogenic Switch

Felsher, Dean W.

Journal:

Lymphatic Research and Biology

Year:

2008

Language:

english

File:

PDF, 617 KB

english, 2008

41

Cancer Therapy: Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy (Small 3/2014)

Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W.,

Journal:

Year:

2014

File:

PDF, 1.85 MB

2014

42

MYC through miR-17-92 Suppresses Specific Target Genes to Maintain Survival, Autonomous Proliferation, and a Neoplastic State

Li, Yulin, Choi, Peter S., Casey, Stephanie C., Dill, David L., Felsher, Dean W.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.21 MB

english, 2014

43

Characterization of MYC-Induced Tumorigenesis by in Situ Lipid Profiling

Perry, Richard H., Bellovin, David I., Shroff, Emelyn H., Ismail, Ali I., Zabuawala, Tahera, Felsher, Dean W., Zare, Richard N.

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

44

SPECT and PET Imaging of EGF Receptors with Site-Specifically Labeled EGF and Dimeric EGF

Levashova, Zoya, Backer, Marina V., Horng, George, Felsher, Dean, Backer, Joseph M., Blankenberg, Francis G.

Journal:

Bioconjugate Chemistry

Year:

2009

Language:

english

File:

PDF, 890 KB

english, 2009

45

Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W.,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.42 MB

english, 2014

46

[IEEE 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Osaka (2013.7.3-2013.7.7)] 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - A tumor-immune mathematical model of CD4+ T helper cell dependent tumor regression by oncogene inactivation

Nwabugwu, Chinyere I., Rakhra, Kavya, Felsher, Dean W., Paik, David S.

Year:

2013

Language:

english

File:

PDF, 1.37 MB

english, 2013

47

[IEEE 2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) - Larnaca, Cyprus (2012.11.11-2012.11.13)] 2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) - Mathematical modeling of the interactions between cellular programs in response to oncogene inactivation: Incorporation of both cell intrinsic and cell extrinsic (Immune mediated) effects

Nwabugwu, Chinyere, Rakhra, Kavya, Felsher, Dean, Paik, David

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

48

Oncogene withdrawal engages the immune system to induce sustained cancer regression

Casey, Stephanie C, Li, Yulin, Fan, Alice C, Felsher, Dean W

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2014

Language:

english

File:

PDF, 670 KB

english, 2014

49

Combined Inactivation of MYC and K-Ras Oncogenes Reverses Tumorigenesis in Lung Adenocarcinomas and Lymphomas

Tran, Phuoc T., Fan, Alice C., Bendapudi, Pavan K., Koh, Shan, Komatsubara, Kim, Chen, Joy, Horng, George, Bellovin, David I., Giuriato, Sylvie, Wang, Craig S., Whitsett, Jeffrey A., Felsher, Dean W.,

Journal:

Year:

2008

Language:

english

File:

PDF, 783 KB

english, 2008

50

Real-time nanoscale proteomic analysis of the novel multi-kinase pathway inhibitor rigosertib to measure the response to treatment of cancer

Fan, Alice C, O'Rourke, Jennifer J, Praharaj, Dave R, Felsher, Dean W

Journal:

Expert Opinion on Investigational Drugs

Year:

2013

Language:

english

File:

PDF, 613 KB

english, 2013

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